BIOL 2415: Cell Biology

1. You will be assigned a number 1-4, those are the questions you have to answer!

2. Read the article/s below to find the answers to the questions.

3. Note or highlight the answers so you can share them with the rest of the class.

Background resources for Cystic Fibrosis:

NHGRI - Cystic Fibrosis

Mayo Clinic - CF Symptoms and Causes

Mayo Clinic - CF Diagnosis and Treatment

1- Symptoms and Disease Presentation

• What parts of the body does this disorder affect?
• How does it affect them?
• What negative outcomes does this produce?

2- Genes and Inheritance

• What gene is affected?
• What is the inheritance pattern?
• How common is this disease?
• How common are carriers of the mutation?

3- Cell Function

• What type of function does the gene product normally have in the cell?
• How does the mutated gene affect this function?
• What does this cause in the affected cells and tissues?

4- Treatment and Diagnosis

• How is this disorder diagnosed?
• What types of treatment are being researched?